Publications

Publications

  1. Doran, M., We need to talk about post-pandemic lectures. Nature, 2021.
  2. Nowlan, B., K. Futrega, E.D. Williams, and M.R. Doran, Human bone marrow-derived stromal cell behavior when injected directly into the bone marrow of NOD-scid-gamma mice pre-conditioned with sub-lethal irradiation (accepted). Stem Cell Research & Therapy, 2021.
  3. Monterosso, M.E., K. Futrega, W.B. Lott, I. Vela, E.D. Williams, and M.R. Doran, Using the Microwell-mesh to culture microtissues in vitro and as a carrier to implant microtissues in vivo into mice. Scientific Reports, 2021. 11(1).
  4. Futrega, K., P.G. Robey, T.J. Klein, R.W. Crawford, and M.R. Doran, A single day of TGF-β1 exposure activates chondrogenic and hypertrophic differentiation pathways in bone marrow-derived stromal cells. Communications Biology, 2021. 4(1).
  5. Futrega, K., E. Music, P.G. Robey, S. Gronthos, R. Crawford, S. Saifzadeh, T.J. Klein, and M.R. Doran, Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo. Stem Cell Res Ther, 2021. 12(1): p. 26.
  6. Doran, M., W. Lott, A. Barnett, J. Leach, and J. Ioannidis, The future of grant proposals is video. Nature, 2021.
  7. Christian, K., C. Johnstone, J.-a. Larkins, W. Wright, and M.R. Doran, A survey of early-career researchers in Australia. eLife, 2021. 10.
  8. Nowlan, B., E.D. Williams, M.R. Doran**, and J.-P. Levesque, CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient-derived strains. Haematologica, 2020. 105(1): p. 71-82. (** co-senior author)
  9. Music, E., T.J. Klein, W.B. Lott, and M.R. Doran, Transforming growth factor-beta stimulates human bone marrow-derived mesenchymal stem/stromal cell chondrogenesis more so than kartogenin. Scientific Reports, 2020. 10(1).
  10. Futrega, K., E. Music, P.G. Robey, S. Gronthos, R.W. Crawford, S. Saifzadeh, T.J. Klein, and M.R. Doran, Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo. Stem Cell Research and Therapy, 2020. Accepted Sept 2020.
  11. Alexander, N., J. Walshe, N.A. Richardson, K. Futrega, M.R. Doran, D.G. Harkin, and A.M.A. Shadforth, Stromal cells cultivated from the choroid of human eyes display a mesenchymal stromal cell (MSC) phenotype and inhibit the proliferation of choroidal vascular endothelial cells in vitro. Experimental Eye Research, 2020. 200.
  12. Music, E., K. Futrega, J.S. Palmer, M. Kinney, B. Lott, T.J. Klein, and M.R. Doran, Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis. Stem Cell Research & Therapy, 2020. 11(1).
  13. Christian, K., C. Johnstone, J.-a. Larkins, W. Wright, and M. Doran. Survey of Australian STEMM Early Career Researchers: Job insecurity and questionable research practices are major structural concerns. preLights 2020; Available from: https://prelights.biologists.com/highlights/survey-of-australian-stemm-early-career-researchers-job-insecurity-and-questionable-research-practices-are-major-structural-concerns/.
  14. Futrega, K., E. Music, P.G. Robey, S. Gronthos, R.W. Crawford, S. Saifzadeh, T.J. Klein, and M.R. Doran, Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo. bioRxiv, 2020.
  15. Christian, K., C. Johnstone, J. Larkins, W. Wright, and M. Doran, What are questionable research practices as reported by ECRs in STEMM in Australia?, 2020: Australasian Human Research Ethics Consultancy Services Pty Ltd (AHRECS), https://ahrecs.com/research-integrity/what-are-questionable-research-practices-as-reported-by-ecrs-in-stemm-in-australia/.
  16. Christian, K., C. Johnstone, J.-a. Larkins, W. Wright, and M.R. Doran, Survey of Australian STEMM Early Career Researchers: job insecurity and questionable research practices are major structural concerns. bioRxiv, 2020.
  17. Futrega, K., P.G. Robey, T.J. Klein, R.W. Crawford, and M.R. Doran, Micro-pellet culture reveals that bone marrow mesenchymal stromal cell (BMSC) chondrogenic induction is triggered by a single day of TGF-beta1 exposure bioRxiv, 2019.
  18. McKenna, E., T.J. Klein, M.R. Doran, and K. Futrega, Integration of an ultra-strong poly(lactic-co-glycolic acid) (PLGA) knitted mesh into a thermally induced phase separation (TIPS) PLGA porous structure to yield a thin biphasic scaffold suitable for dermal tissue engineering. Biofabrication, 2019. 12(1): p. 015015.
  19. Mosaad, E.O., K. Futrega, I. Seim, B. Gloss, K.F. Chambers, J.A. Clements, and M.R. Doran, Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design. Sci Rep, 2019. 9(1): p. 11334.
  20. Nowlan, B., E.D. Williams, M.R. Doran**, and J.P. Levesque, CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica, 2019. (** co-senior author)
  21. Mosaad, E., K. Chambers, K. Futrega, J. Clements, and M.R. Doran, Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures. BMC Cancer, 2018. 18(1): p. 592.
  22. Music, E., K. Futrega, and M.R. Doran, Sheep as a model for evaluating mesenchymal stem/stromal cell (MSC)-based chondral defect repair. Osteoarthritis Cartilage, 2018.
  23. Mosaad, E.O., K.F. Chambers, K. Futrega, J.A. Clements, and M.R. Doran, The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform. Sci Rep, 2018. 8(1): p. 253.
  24. Mosaad, E.M., K.F. Chambers, K. Futrega, J.A. Clements, and M.R. Doran, Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures.BMC Cancer, 2018. (in press).
  25. Brooks, A., K. Futrega, X. Liang, X. Hu, X. Liu, D.H.G. Crawford, M.R. Doran, M.S. Roberts, and H. Wang, Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Transl Med, 2018. 7(1): p. 78-86.
  26. Nowlan, B., K. Futrega, M.E. Brunck, G. Walkinshaw, L.E. Flippin, M.R. Doran**, and J.P. Levesque, HIF-1alpha-stabilizing agent FG-4497 rescues human CD34(+) cell mobilization in response to G-CSF in immunodeficient mice. Exp Hematol, 2017. 52: p. 50-55 e6. **co-senior author
  27. Michl, T.D., C. Giles, P. Mocny, K. Futrega, M.R. Doran, H.A. Klok, H.J. Griesser, and B.R. Coad, Caspofungin on ARGET-ATRP grafted PHEMA polymers: Enhancement and selectivity of prevention of attachment of Candida albicans. Biointerphases, 2017. 12(5): p. 05G602.
  28. Futrega, K., K. Atkinson, W.B. Lott, and M.R. Doran, Spheroid Coculture of Hematopoietic Stem/Progenitor Cells and Monolayer Expanded Mesenchymal Stem/Stromal Cells in Polydimethylsiloxane Microwells Modestly Improves In Vitro Hematopoietic Stem/Progenitor Cell Expansion. Tissue Eng Part C Methods, 2017. 23(4): p. 200-218.
  29. Doran, M., A. Barnett, J. Leach, W. Lott, K. Page, and W. Grant, Can video improve grant review quality and lead to more reliable ranking? . Research Ideas and Outcomes 3: e11931., 2017. 3(e11931).
  30. Pelekanos, R.A., V.S. Sardesai, K. Futrega, W.B. Lott, M. Kuhn, and M.R. Doran, Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue. J Vis Exp, 2016(112).
  31. Doran, M., How to survive as a whistle-blower. Nature, 2016. 532(7599): p. 405-405.
  32. Futrega, K., J. Yu, J.W. Jones, M.A. Kane, W.B. Lott, K. Atkinson, and M.R. Doran, Polydimethylsiloxane (PDMS) modulates CD38 expression, absorbs retinoic acid and may perturb retinoid signalling. Lab Chip, 2016. 16(8): p. 1473-83.
  33. Futrega, K., W.B. Lott, and M.R. Doran, Direct bone marrow HSC transplantation enhances local engraftment at the expense of systemic engraftment in NSG mice. Sci Rep, 2016. 6: p. 23886.
  34. Atkinson, K., N. Timmins, G.C. Kiel, C. Heazlewood, M.R. Doran, and G. Brooke, Closed automated large-scale bioreactors for manufacturing mesenchymal stromal cells for clinical use, in The Biology and Therapeutic Application of Mesenchymal Cells, K. Atkinson, Editor. 2016, John Wiley and Sons Inc: NJ. p. 616-618.
  35. Osiecki, M.J., T.D. Michl, B. Kul Babur, M. Kabiri, K. Atkinson, W.B. Lott, H.J. Griesser, and M.R. Doran, Packed Bed Bioreactor for the Isolation and Expansion of Placental-Derived Mesenchymal Stromal Cells. PLoS One, 2015. 10(12): p. e0144941.
  36. Michl, T.D., B.R. Coad, M.R. Doran, M. Osiecki, M.H. Kafshgari, N.H. Voelcker, A. Hüsler, K. Vasilev, and H.J. Griesser, Nitric oxide releasing plasma polymer coating with bacteriostatic properties and no cytotoxic side effects. Chemical Communications, 2015. 51(32): p. 7058-7060
  37. Futrega, K., J.S. Palmer, M. Kinney, W.B. Lott, M.D. Ungrin, P.W. Zandstra, and M.R. Doran, The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues. Biomaterials, 2015. 62: p. 1-12.
  38. Babur, B.K., M. Kabiri, T.J. Klein, W.B. Lott, and M.R. Doran, The rapid manufacture of uniform composite multicellular-biomaterial micropellets, their assembly into macroscopic organized tissues, and potential applications in cartilage tissue engineering. PLoS One, 2015. 10(5): p. e0122250.
  39. Babur, B.K., K. Futrega, W.B. Lott, T.J. Klein, J. Cooper-White, and M.R. Doran, High-throughput bone and cartilage micropellet manufacture, followed by assembly of micropellets into biphasic osteochondral tissue. Cell Tissue Res, 2015. 361(3): p. 755-68.
  40. Tseng, L.P., C.Y. Juan, S.L. Lin, M.R. Doran, J.J. Lin, S.H. Hsu, J.W. Liao, C.I. Shen, and H.L. Su, Nanohybrids of silver particles on clay platelets delaminate Pseudomonas biofilms. Nanomedicine (Lond), 2014. 9(7): p. 1019-33.
  41. Saha, P.S. and M.R. Doran, Different in Vitro Activation Methods for Latent Transforming Growth Factors (TGF)–β: Considerable Exogenous Factors to Promote Higher Mesenchymal-Origin Cell Proliferation in a Bioprocessing Platform. Biomedical Science and Engineering, 2014. 2(1): p. 5-12.
  42. Michl, T.D., B.R. Coad, M.R. Doran, A. Hüsler, J.D.P. Valentin, K. Vasilev, and H.J. Griesser, Plasma polymerization of 1,1,1-trichloroethane yields a coating with robust antibacterial surface properties. RSC Advances, 2014(4): p. 27604-27606
  43. Futrega, K., M. King, W.B. Lott, and M.R. Doran, Treating the whole not the hole: necessary coupling of technologies for diabetic foot ulcer treatment. Trends Mol Med, 2014. 20(3): p. 137-42.
  44. Doran, M.R., W.B. Lott, and S.E. Doran, (Video Publication) TIBS Science & Society: Multimedia for grant applications. Trends Biochemical Sciences, 2014. 39(4): p. https://www.cell.com/doi/story/10.1016/vid.2015.07.16.2223?code=cell-site.
  45. Doran, M.R., W.B. Lott, and S.E. Doran, Multimedia: a necessary step in the evolution of research funding applications. Trends Biochem Sci, 2014. 39(4): p. 151-3.
  46. Doran, M.R., W.B. Lott, and S.E. Doran, Communication: Use multimedia in grant applications. Nature, 2014. 505(7483): p. 291.
  47. Chambers, K.F., E.M. Mosaad, P.J. Russell, J.A. Clements, and M.R. Doran, 3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer. PLoS One, 2014. 9(11): p. e111029.
  48. Young, M. and M.R. Doran, Mesenchymal stem cell therapies for bone and tendon conditions, in Mesenchymal Stem Cell Therapy, L.G. Chase and M.C. Vemuri, Editors. 2013, Springer: New York.
  49. Lott, W.B. and M.R. Doran, Do RNA viruses require genome cyclisation for replication? Trends Biochem Sci, 2013. 38(7): p. 350-5.
  50. Kabiri, M., W.B. Lott, E. Kabiri, P.J. Russell, and M.R. Doran, In Vitro Assessment of Migratory Behavior of Two Cell Populations in a Simple Multichannel Microdevice. Processes, 2013. 1(3): p. 349-359.
  51. Doran, M.R. and M. Young, Mesenchymal stromal cells and the repair of cartilage tissue, in Mesenchymal Stem Cell Therapy, L.G. Chase and M.C. Vemuri, Editors. 2013, Springer: New York. p. 145-160.
  52. Doran, M.R. and W.B. Lott, A duty of care. Trends Biochem Sci, 2013. 38(1): p. 1-2.
  53. Cook, M.M., M.R. Doran, K. Kollar, V. Barbier, I.G. Winkler, J.P. Levesque, G. Brooke, and K. Atkinson, Engraftment Outcomes after HPC Co-Culture with Mesenchymal Stromal Cells and Osteoblasts. J Clin Med, 2013. 2(3): p. 115-35.
  54. Babur, B.K., P. Ghanavi, P. Levett, W.B. Lott, T. Klein, J.J. Cooper-White, R. Crawford, and M.R. Doran, The interplay between chondrocyte redifferentiation pellet size and oxygen concentration. PLoS One, 2013. 8(3): p. e58865.
  55. Timmins, N.E., M. Kiel, M. Gunther, C. Heazlewood, M.R. Doran, G. Brooke, and K. Atkinson, Closed system isolation and scalable expansion of human placental mesenchymal stem cells. Biotechnol Bioeng, 2012. 109(7): p. 1817-26.
  56. Kabiri, M., M. Soleimani, I. Shabani, K. Futrega, N. Ghaemi, H.H. Ahvaz, E. Elahi, and M.R. Doran, Neural differentiation of mouse embryonic stem cells on conductive nanofiber scaffolds. Biotechnol Lett, 2012. 34(7): p. 1357-65.
  57. Kabiri, M., B. Kul, W.B. Lott, K. Futrega, P. Ghanavi, Z. Upton, and M.R. Doran, 3D mesenchymal stem/stromal cell osteogenesis and autocrine signalling. Biochem Biophys Res Commun, 2012. 419(2): p. 142-7.
  58. Ghanavi, P., M. Kabiri, and M.R. Doran, The rationale for using microscopic units of a donor matrix in cartilage defect repair. Cell Tissue Res, 2012. 347(3): p. 643-8.
  59. Doran, M.R., I.A. Aird, F. Marturana, N. Timmins, K. Atkinson, and L.K. Nielsen, Bioreactor for blood product production. Cell Transplant, 2012. 21(6): p. 1235-44.
  60. Cook, M.M., K. Futrega, M. Osiecki, M. Kabiri, B. Kul, A. Rice, K. Atkinson, G. Brooke, and M. Doran, Micromarrows–three-dimensional coculture of hematopoietic stem cells and mesenchymal stromal cells. Tissue Eng Part C Methods, 2012. 18(5): p. 319-28.
  61. Futrega, K., D. Leavesley, and M.R. Doran, A brief history of haemotopoietic stem cell Ex vivo expansion.Australian Biochemist, 2011. 42(3): p. 5-7.
  62. Prowse, A.B., M.R. Doran, J.J. Cooper-White, F. Chong, T.P. Munro, J. Fitzpatrick, T.L. Chung, D.N. Haylock, P.P. Gray, and E.J. Wolvetang, Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media. Biomaterials, 2010. 31(32): p. 8281-8.
  63. Osiecki, M., P. Ghanavi, K. Atkinson, L.K. Nielsen, and M.R. Doran, The ascorbic acid paradox. Biochem Biophys Res Commun, 2010. 400(4): p. 466-70.
  64. Markway, B.D., G.K. Tan, G. Brooke, J.E. Hudson, J.J. Cooper-White, and M.R. Doran, Enhanced chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in low oxygen environment micropellet cultures. Cell Transplant, 2010. 19(1): p. 29-42.
  65. Doran, M.R., B.D. Markway, A. Clark, S. Athanasas-Platsis, G. Brooke, K. Atkinson, L.K. Nielsen, and J.J. Cooper-White, Membrane bioreactors enhance microenvironmental conditioning and tissue development.Tissue Eng Part C Methods, 2010. 16(3): p. 407-15.
  66. Doran, M.R., J.E. Frith, A.B. Prowse, J. Fitzpatrick, E.J. Wolvetang, T.P. Munro, P.P. Gray, and J.J. Cooper-White, Defined high protein content surfaces for stem cell culture. Biomaterials, 2010. 31(19): p. 5137-42.
  67. George, P.A., M.R. Doran, T.I. Croll, T.P. Munro, and J.J. Cooper-White, Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly. Biomaterials, 2009. 30(27): p. 4732-7.
  68. Doran, M.R., R.J. Mills, A.J. Parker, K.A. Landman, and J.J. Cooper-White, A cell migration device that maintains a defined surface with no cellular damage during wound edge generation. Lab Chip, 2009. 9(16): p. 2364-9.
  69. Doran, M.R., B.D. Markway, T.I. Croll, S. Sara, T.P. Munro, and J.J. Cooper-White, Controlled presentation of recombinant proteins via a zinc-binding peptide-linker in two and three dimensional formats. Biomaterials, 2009. 30(34): p. 6614-20.
  70. Doran, M.R., B.D. Markway, I.A. Aird, A.S. Rowlands, P.A. George, L.K. Nielsen, and J.J. Cooper-White, Surface-bound stem cell factor and the promotion of hematopoietic cell expansion. Biomaterials, 2009. 30(25): p. 4047-52.
  71. Chau, L., M. Doran, and J. Cooper-White, A novel multishear microdevice for studying cell mechanics. Lab Chip, 2009. 9(13): p. 1897-902.
  72. Lauto, A., J. Hook, M. Doran, F. Camacho, L.A. Poole-Warren, A. Avolio, and L.J. Foster, Chitosan adhesive for laser tissue repair: in vitro characterization. Lasers Surg Med, 2005. 36(3): p. 193-201.
  73. Doran, M.R. and P. Choi, Molecular dynamics studies of the effects of branching characteristics on the crystalline structure of polyethylene. The Journal of Chemical Physics, 2001. 115(6): p. 2827-2830.

Patents

  1. Nordon, Doran, Deppisch. Device and method to prevent culture media degradation. WO Patent 2,006,026,835 2006.
  2. Doran, Cooper-White. Microbioreactor. WO Patent 2,008,028,241. 2008.
  3. Cooper-White, Doran, Mills. Cell migration. WO Patent 2,010,078,623. 1. 2010.
  4. Michl, Doran, Osiecki, Vasliev, Griesser, Bacteriostatic surfaces, 2014902149. 2014.
  5. Doran and Futrega, Microwells and diabetes. 2019